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2 Pack / TUBE

Inside each tube, three powerful vitamins blend with expert-selected ingredients to keep your mouth in check. It’s a multi-tasking, mouth-loving toothpaste that tastes great and works even better.

  • Whitens teeth
  • Protects against sensitivity
  • Prevents cavities + remineralizes enamel
  • Infused with Aloe and Vitamin A, Vitamin C, Vitamin E
  • SLS Free!
  • Balanced 7.0 pH. Just how your mouth likes it
Cooling Spearmint Eucalyptus (2-Pack)
  • Variety Pack (3-Pack)
  • Cooling Spearmint Eucalyptus (2-Pack)
  • Invigorating Wintergreen & Peppermint (2-Pack)
  • Calming Vanilla Lavender Mint (2-Pack)
  • Classic Duo (2-Pack)

Try risk-free, 100% smiles guaranteed

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Fluoride for cavity prevention and Potassium nitrate for sensitivity relief


Formulated and loved by world class oral health experts


Always made clean. Never made with SLS


Twice is a balanced 7.0 pH. Just how your mouth likes it


Dentist approved for safe & effective whitening


Vitamin A, C, E and Aloe Vera help soothe & hydrate gums

Potassium Nitrate, Sodium Fluoride, Hydrated Silica, Sorbitol, Glycerin, Pentasodium Triphosphate, Cocamidopropyl Betaine, Sodium Ascorbyl Phosphate (Vitamin C), Retinyl Palmitate (Vitamin A), Tocopherol (Vitamin E), Aloe Barbadensis Leaf Juice (Aloe Vera), Flavor, Lauryl Glucoside, Sodium Saccharin, Xylitol, Sucralose, Cellulose Gum, Titanium Dioxide, Sodium Benzoate, Citric Acid, Water.

Twice vs Others




Sensitivity Relief

Cavity Prevention

Mouth-Healthy Vitamins

SLS Free

100% Recyclable

Vegan / Cruelty Free

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marble Mint


Multifunctional benefits that give your teeth and mouth what they’ve been missing, plus clean ingredients that are better for your body. Part science. Part wellness. All good.

Refreshingly real reviews

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Vitamins in toothpaste? What do they do?


Yes! We spent almost 2 years working with world-class oral health experts and dental professionals on a mission to make toothpaste for complete oral wellness. We eventually found and selected three powerful, antioxidant vitamins that your mouth loves. Vitamin A, Vitamin C, and Vitamin E combine to balance bacteria, promote saliva production (and limit dry mouth), hydrate and strengthen your gums, fight free radicals, and work to maintain overall health in the ecosystem that is your mouth.

Why is this different from “regular” toothpaste?


Even though Twice may look like familiar toothpastes, it is completely different. The secret starts with our philosophy - that a healthy mouth is a healthy body. Twice toothpaste does much more than just whiten teeth and freshen breath. This is a true all-in-one toothpaste filled with multi-functional benefits that provide complete care for all teeth. Thoughtfully selected one-of-a-kind vitamins and antioxidants are infused for the benefits to your oral microbiome (your mouth), and your body. A 7.0 neutral pH helps ensure oral health balance and limit potential inflammation. And at less than a quarter per day, you get the benefits of living healthier at affordable prices.

What is a 100% Smiles Guarantee?


If you're not completely in love with your toothpaste, we'll refund your first tube in full.

Is this toothpaste vegan?


Yes. Twice is perfect for anyone looking for vegan and cruelty-free products. Did you know some toothpaste contains ingredients derived from sources like animal fats? Our ingredients, like Glycerin, are derived from vegetables.

We love our animals. The Twice HQ is packed with pets :). We are Leaping Bunny certified because we will take this seriously and would never test anything on our furry friends.

Do kids like/use Twice?


Absolutely! We recommend any child that does not swallow their toothpaste to use Twice. We hear from parents all the time - kids love our flavors and they remember to brush Twice! Nothing makes us happier than a family prioritizing oral health and practicing better habits together.

What are sulfates?


Not all foam is your friend. Do you remember the bubbles that fill your mouth when you brush your teeth? How could you forget, right!? Well, sulfates are the ingredients that cause that foam. Most sulfates, like Sodium Lauryl Sulfate, are known irritants which will dry the mouth, cause irritation, and can lead to canker sores and even infection. An untreated infection can lead to life-threatening disease - there is nothing healthy about sulfates. The ingredients in Twice toothpaste that help create foam are derived from plants - we will never use sulfates.

How big is a tube of Twice toothpaste?


100 ml or 3.4 ounces. That means it should last about 2 months, and is also travel friendly! No need for additional mini tubes on your next trip.

What’s the best way for me to get Twice?


Subscribe! It’s the cheapest, ensures you never run out, and it is super easy to manage yourself. Want to pause, cancel, skip? Easy. Update information, change the products in the subscription or change the frequency of delivery? Easy. We would love to have you as a subscriber :)

Does this toothpaste whiten?


Yes! Our chief formulator and oral health expert is the unofficial godfather of teeth whitening. He holds over 20 patents on teeth whitening technologies. In Twice toothpaste, there are two methods of teeth whitening that occurs over time as you brush. There is mechanical removal of plaque through our gentle-yet-effective silicates, and there is safe chemical removal of plaque through our special ingredient pentasodium triphosphate. The result is a super-clean, glistening smile after every brush. Of course, different teeth may have different levels of results - it can take 2 - 4 weeks to start seeing the effect.

My teeth get sensitive! Does this toothpaste help me?


Absolutely! One active ingredient in Twice is Potassium Nitrate, commonly found in the leading sensitivity protection toothpastes. Twice works hard to protect your teeth because we know there is nothing more painful than a bad reaction to hot/cold or sweet/sour. Our ingredients work to build up protection over time so that you can enjoy that ice cream pain-free.

My teeth need fluoride for protection, does your toothpaste have that?


Yes! Twice was formulated and created with world-class oral health experts. To them, Fluoride is the #1 ingredient to strengthen teeth and prevent painful cavities and decay. Twice has a moderate and safe level of fluoride, so use as directed and keep smiling.

Do you ship internationally?


We offer fast and affordable international shipping to customers around the world on www.shopmayple.com.

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