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Mouthwash is a great way to reduce the risk of cavities and gum disease when paired with regular brushing and flossing. However, many mouthwashes are packed with chemicals that can be harsh on sensitive oral tissues and even cause a burning sensation. As a result, many consumers choose oral rinses with ingredients that are gentler on the mouth while still effectively cleaning and protecting.

We'll be putting two popular alcohol- and SLS-free mouthwash options head-to-head: Twice Oral Wellness Immunity Rinse and TheraBreath ​​Fresh Breath Oral Rinse. Let’s find out which mouthwash is right for you!

Twice Oral Wellness Immunity Rinse vs. TheraBreath ​​Fresh Breath Oral Rinse

TheraBreath ​​Fresh Breath Oral Rinse

Twice Oral Wellness Immunity Rinse

Main Ingredients

Sodium Chlorite, Tetrasodium EDTA, Sodium Benzoate, Baking Soda, Flavor, Sodium Hydroxide

Colloidal Silver, Zinc, Hydrogen Peroxide, Baking Soda, Aloe Vera, Coconut Oil, Spirulina

Benefits

Formulated specifically to fight bad breath; pH balanced, non-burning formula

Enhances natural defenses, supports healthy oral microbiome, soothes minor oral wounds, fights bad breath and plaque

Flavor

Mild mint is flavored with peppermint oil (other flavors are available)

Flavored with peppermint oil/extract and cinnamon extract

Alcohol Content

Alcohol-Free

Alcohol-Free

Packaging

Similar to traditional mouthwash bottle with measuring cap

Sleek, travel-friendly bottle with pressable nozzle

Value

16 oz bottle lasts up to 11 days when used as directed

3.4 oz bottle lasts up to 30 days when used as directed


Ingredients

TheraBreath

TheraBreath Fresh Breath Oral Rinse’s ingredients list is fairly straightforward and accessible. The formula contains Water, PEG-40 Hydrogenated Castor Oil, Sodium Chlorite, Tetrasodium EDTA, Sodium Benzoate, Sodium Bicarbonate, Mentha Piperita (Peppermint) Oil and Sodium Hydroxide. Sodium Chlorite, in particular, is an oxidizing agent that helps to neutralize odor-causing compounds, giving this rinse its breath-freshening qualities. Sodium Bicarbonate, better known as baking soda, can neutralize harmful acids in the mouth1 and help to remove surface stains from teeth.2 TheraBreath also contains no artificial dyes and is certified kosher, vegan and gluten-free.

Twice Mouthwash

Twice Oral Wellness Immunity Rinse combines a blend of natural and scientifically-backed ingredients split into a two-part formula. Part A contains ingredients like hydrogen peroxide, known for its powerful antibacterial and antimicrobial properties,3 and peppermint leaf extract and oil, which provide a fresh, natural flavor.

Part B includes Zinc, which fights bad breath4 and plaque,5 and baking soda (like in TheraBreath) to elevate oral pH and neutralize bacteria. Interestingly, Twice also features natural ingredients like coconut oil, known to reduce oral bacteria;6 aloe extract, which has soothing properties;7 and spirulina, known to help reduce dental plaque and inflammation.8

A standout ingredient in Twice's formulation is colloidal silver, which supports natural immune defenses and reduces biofilm buildup.9 Like TheraBreath, Twice excludes alcohol, SLS, gluten, animal products and artificial dyes from its product.

Key Takeaways

  • Both are SLS-free, free from artificial dye, vegan and gluten-free
  • Both contain sodium bicarbonate as an active ingredient
  • Both contain peppermint oil for flavoring

TheraBreath:

  • Contains Water, PEG-40 Hydrogenated Castor Oil, Sodium Chlorite, Tetrasodium EDTA, Sodium Benzoate, Sodium Bicarbonate, Flavor, Sodium Hydroxide

Twice Mouthwash:

  • Features natural ingredients like Colloidal Silver, Zinc, Aloe Vera and Coconut Oil
  • Twice contains more ingredients overall as it uses a two-part formula to clean and protect teeth.

    Uses and Benefits

    TheraBreath

    TheraBreath was specifically formulated to combat halitosis (also known as bad breath). As such, most of its active ingredients are focused on eliminating the bacteria that cause unpleasant odors.10 The company recommends rinsing with one capful and gargling a second every 12 hours after brushing and flossing. For best results, they recommend using in combination with TheraBreath Toothpaste and not rinsing in between.11

    Twice Mouthwash

    Twice Oral Wellness Immunity Rinse is designed to promote general oral health by enhancing your mouth's natural defenses and supporting a balanced and healthy oral microbiome. It can also be used to clean minor oral wounds (such as following a dental procedure) and canker sores without drying or irritation. Twice suggests rinsing for 15 seconds after brushing twice a day and after meals.

    Key Takeaways

    TheraBreath:

    • Designed to treat halitosis when used twice daily

    Twice Mouthwash:

    • Enhances natural defenses and supports a healthy oral microbiome
    • Can be used to cleanse minor oral wounds and canker sores

      Flavor

      TheraBreath

      The original Fresh Breath Oral Rinse flavor is Mild Mint, which gets its flavor from peppermint oil. TheraBreath offers a wide range of minty flavors for adults, like Sparkling Mint, Invigorating Icy Mint and Clean Mint, along with flavors like Grapes Galore, Strawberry Splash and Wacky Watermelon for mouthwash products designed for children. They state that they do not use artificial flavors in any of their products.

      Twice Mouthwash

      Similar to Mild Mint, Twice Oral Wellness Immunity Rinse has a mild peppermint flavor thanks to peppermint oil and extract. It also includes cinnamon extract, which adds a hint of spice to the flavor and may aid in fighting gum disease.12 Twice also excludes artificial flavorings, relying on natural ingredients like coconut oil and aloe vera for a balanced flavor profile without being overpoweringly minty or artificially sweet.

      Key Takeaways

      TheraBreath:

      • Offers a range of minty and fruity flavors in addition to original Mild Mint
      • No artificial flavors

      Twice Mouthwash:

      • Offers one mild, minty flavor
      • No artificial flavors

        Alcohol Content

        TheraBreath

        TheraBreath mouthwash does not include alcohol.

        Twice Mouthwash

        Twice Oral Wellness Immunity Rinse is also alcohol-free.

        Key Takeaways

         

        • Neither Twice nor TheraBreath mouthwash contains alcohol.

        Packaging

        TheraBreath

        TheraBreath Fresh Breath Oral Rinse comes in a classic-shaped bottle with a screw-on dosage cap that can be used to measure out your rinse. It comes in two main sizes: a 16-oz bottle and a 1-liter bottle. They also offer a 3 oz travel-size bottle for on-the-go.

        Twice Mouthwash

        Twice Oral Wellness Immunity Rinse offers a sleek, modern, travel-friendly bottle design. The product’s dual-action formula is separated into two parts, requiring you to shake before use. In lieu of a dosage cap, the bottle features a pressable nozzle for dispensing a single dose of the product directly into the mouth, adding to the convenience and hygiene of use. While Twice only offers one packaging size, it measures in at a TSA-approved 3.4 oz.

        Key Takeaways

        TheraBreath:

        • Classic-shaped bottle with a dosage cap
        • Offers travel-size bottles in addition to standard 16oz and 1L bottles.


        Twice Mouthwash:

        • Travel-friendly 3.4 oz bottle
        • Features a pressable nozzle for direct dispensing without measuring

          Value

          TheraBreath

          TheraBreath states that the odor-fighting effects of its Fresh Breath Oral Rinse should last 12 hours after use. When used as directed, a 16 oz bottle of TheraBreath should last up to 11 days. Their FAQs state that most consumers will use 2-3 bottles per month. At $9.95 per bottle, a 30-day supply comes in at around $27.14.

          Twice Mouthwash

          A single 3.4 oz bottle of Twice Oral Wellness Immunity Rinse is designed to last 30 days when used as directed. At $19.99 per bottle, a month’s supply of Twice Oral Wellness Immunity Rinse is more affordable than a month’s supply of TheraBreath Fresh Breath Oral Rinse. Combined with its convenient and recyclable packaging, Twice mouthwash is a worthwhile investment for those seeking a high-performing, long-lasting and holistically focused oral care product.

          Key Takeaways

          • Both products offer a 30-day money-back guarantee if you are not satisfied with your purchase

          TheraBreath

          • One 16 oz bottle lasts 11 days when used as directed
          • Most people use 2-3 bottles each month
          • A 30-day supply costs around $27.14.

          Twice Mouthwash:

          • One 3.4 oz bottle lasts 30 days when used as directed
          • A 30-day supply costs around $19.99.
            Packaging for Oral Wellness Immunity Rinse. Text reads: "Vegan, sulfate & SLS free, cruelty free, non-GMO, BPA free, no artificial dyes, made in the USA, recyclable packaging"

              The Bottom Line

              Both TheraBreath Fresh Breath Oral Rinse and Twice Oral Wellness Immunity Rinse have their own unique strengths as part of a complete oral care routine. Ultimately, your choice of product comes down to your personal oral health goals and preferences.

              For individuals looking to specifically treat bad breath, it would be hard to go wrong with a product like TheraBreath. But for a more holistic approach to oral wellness, Twice Oral Wellness Immunity Rinse offers well-rounded protection and odor-fighting ingredients for a better smile.

              Shop Oral Wellness Immunity Rinse

              This page was written or reviewed for accuracy by the Twice Team. Learn more about us.

              Sources:

              1. National Journal of Maxillofacial Surgery - The effect of sodium bicarbonate oral rinse on salivary pH and oral microflora: A prospective cohort study
              2. The Journal of Clinical Dentistry - Laboratory assessment of tooth whitening by sodium bicarbonate dentifrices
              3. International Journal of Dentistry - A Systematic Review of the Effect of Oral Rinsing with H2O2 on Clinical and Microbiological Parameters Related to Plaque, Gingivitis, and Microbes
              4. Journal of Applied Oral Science - Two mechanisms of oral malodor inhibition by zinc ions
              5. Compendium of Continuing Education in Dentistry - Antiplaque/antigingivitis efficacy and safety of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel. Results of a 6-month clinical trial
              6. Nigerian Medical Journal - Effect of coconut oil in plaque related gingivitis — A preliminary report
              7. Journal of Indian Society of Periodontology - Aloe vera: It's effect on gingivitis
              8. International Journal of Pharmacy and Pharmaceutical Sciences - Effectiveness of spirulina mouthwash on reduction of dental plaque and gingivitis: a clinical study
              9. ACS Applied Materials & Interfaces - Taking the Silver Bullet Colloidal Silver Particles for the Topical Treatment of Biofilm-Related Infections
              10. Clinical and Experimental Dental Research - Efficacy of chlorine dioxide mouthwash in reducing oral malodor: A 2‐week randomized, double‐blind, crossover study
              11. TheraBreath - Frequently Asked Questions
              12. Journal of the International Academy of Periodontology - Effect of Cinnamon Extract and Chlorhexidine Gluconate (0.2%) on the Clinical Level of Dental Plaque and Gingival Health: A 4-Week, Triple-Blind Randomized Controlled Trial